Hi I understand that version 129 of dbSNP is considered clean and does not share data from other databases such as 1000G projects.
What steps of the variant calling in WGS/WES analysis can be affected by using GATK resource bundle provided dnSNP138 after excluding the sites released after version 129 versus using all variants in the dbSNP version 138 ?
Are there any specific drawbacks of using latest dbSNP version 150 ?